Please use this identifier to cite or link to this item: http://cris.utm.md/handle/5014/295
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dc.contributor.authorBRANISTE, Tudoren_US
dc.contributor.authorCOBZAC, Vitalieen_US
dc.contributor.authorABABII, Polinaen_US
dc.contributor.authorPLESCO, Irinaen_US
dc.contributor.authorRAEVSCHI, Simionen_US
dc.contributor.authorDIDENCU, Alexandruen_US
dc.contributor.authorNACU, Viorelen_US
dc.contributor.authorABABII, Ionen_US
dc.contributor.authorTIGINYANU, Ionen_US
dc.date.accessioned2020-04-03T10:08:00Z-
dc.date.available2020-04-03T10:08:00Z-
dc.date.issued2020-
dc.identifier.citationTudor Braniste, Vitalie Cobzac, Polina Ababii, Irina Plesco, Simion Raevschi, Alexandru Didencu, Mihail Maniuc, Viorel Nacu, Ion Ababii, Ion Tiginyanu, Mesenchymal stem cells proliferation and remote manipulation upon exposure to magnetic semiconductor nanoparticles, Biotechnology Reports, Volume 25, 2020, e00435, ISSN 2215-017X, https://doi.org/10.1016/j.btre.2020.e00435. (http://www.sciencedirect.com/science/article/pii/S2215017X19304710) Abstract: In this paper, we report on spatial redistribution of bone marrow mesenchymal stem cells loaded with magnetic nanoparticles under the influence of continuously applied magnetic field. Semiconductor nanoparticles were synthesized by epitaxial growth of a GaN thin layer on magnetic sacrificial core consisting of ZnFe2O4 nanoparticles. Different quantities of nanoparticles were incubated in vitro with mesenchymal stem cells. High density of nanoparticles (50 μg/ml) leads to a decrease in the number of cells during incubation, while the density of nanoparticles as low as 10 μg/ml is enough to drag cells in culture and rearrange them according to the spatial distribution of the magnetic field intensity. Keywords: Mesenchymal stem cells; Nanoparticles; Gallium nitride; Cells guidingen_US
dc.identifier.issn2215017X-
dc.identifier.urihttp://cris.utm.md/handle/5014/295-
dc.description.abstractIn this paper, we report on spatial redistribution of bone marrow mesenchymal stem cells loaded with magnetic nanoparticles under the influence of continuously applied magnetic field. Semiconductor nanoparticles were synthesized by epitaxial growth of a GaN thin layer on magnetic sacrificial core consisting of ZnFe2O4 nanoparticles. Different quantities of nanoparticles were incubated in vitro with mesenchymal stem cells. High density of nanoparticles (50 μg/ml) leads to a decrease in the number of cells during incubation, while the density of nanoparticles as low as 10 μg/ml is enough to drag cells in culture and rearrange them according to the spatial distribution of the magnetic field intensity.en_US
dc.language.isoenen_US
dc.relation19.80012.50.03A. Elaborarea suprafețelor cu grad controlat de hidrofobie datorită nanomicrostructurăriien_US
dc.relationNanoMedTwin - Promoting smart specialization at the Technical University of Moldova by developing the field of Novel Nanomaterials for BioMedical Applications through excellence in research and twinningen_US
dc.relation20.80009.50007.20en_US
dc.relation.ispartofBiotechnology Reportsen_US
dc.subjectmesenchymal stem cellsen_US
dc.subjectnanoparticlesen_US
dc.subjectgallium nitrideen_US
dc.subjectcells guidingen_US
dc.titleMesenchymal stem cells proliferation and remote manipulation upon exposure to magnetic semiconductor nanoparticlesen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.btre.2020.e00435-
dc.identifier.scopus2-s2.0-85079424143-
item.grantfulltextopen-
item.languageiso639-1other-
item.fulltextWith Fulltext-
crisitem.author.deptDepartment of Microelectronics and Biomedical Engineering-
crisitem.author.deptDepartment of Microelectronics and Biomedical Engineering-
crisitem.author.orcid0000-0001-6043-4642-
crisitem.author.orcid0000-0003-0893-0854-
crisitem.author.parentorgFaculty of Computers, Informatics and Microelectronics-
crisitem.author.parentorgFaculty of Computers, Informatics and Microelectronics-
crisitem.project.grantno810652-
crisitem.project.grantno20.80009.5007.20.-
crisitem.project.projectURLhttp://nanomedtwin.eu/-
crisitem.project.fundingProgramYoung Researchers Program-
crisitem.project.fundingProgramH2020-EU.4.b.-
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