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Title: Evaluation of ultrasound application for the decellularization of small caliber vessels
Authors: MALCOVA, Tatiana 
NACU, Viorel 
ANDREE, Birgit 
Keywords: decellularization;small caliber vascular grafts;ultrasound;detergent;histological assessment
Issue Date: 2022
Publisher: Springer
Project: 20.80009.5007.20. Nanoarhitecturi în bază de GaN şi matrici tridimensionale din materiale biologice pentru aplicaţii în microfluidică şi inginerie tisulară 
NanoMedTwin - Promoting smart specialization at the Technical University of Moldova by developing the field of Novel Nanomaterials for BioMedical Applications through excellence in research and twinning 
Series/Report no.: IFMBE, volume 87;
Conference: ICNBME-2021
Decellularized matrices for tissue engineering seem to be an attractive material for providing biological vascular grafts for patients with advanced peripheral arterial disease who require bypass surgery, but do not have suitable autologous small-caliber vessels (˂6 mm diameter). Currently, a variety of decellularization (DC) techniques have been proposed such as physical, chemical, and/or enzymatic methods; however, identifying an optimal protocol resulting in preservation of favorable physiochemical properties of the vascular scaffold is still elusive.
Appears in Collections:Proceedings Papers

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